Person who experienced the adverse event (patient)
| Event ID | CASEID | CASEVERSION | I F COD | EVENT DT | MFR DT | INIT FDA DT | FDA DT | REPT COD | AUTH NUM | MFR NUM | MFR SNDR | LIT REF | AGE | AGE COD | AGE GRP | GNDR COD | E SUB | WT | WT COD | REPT DT | TO MFR | OCCP COD | REPORTER COUNTRY | OCCR COUNTRY |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 125244842 | 12524484 | 2 | F | 20160708 | 20160704 | 20160722 | EXP | US-AUROBINDO-AUR-APL-2016-08358 | AUROBINDO | WEISBERG LS. METFORMIN/EPINEPHRINE/NOREPINEPHRINE LACTIC ACIDOSIS: CASE REPORT. REACTIONS WEEKLY. 2016;1606:106 | 0.00 | Y | 0.00000 | 20160722 | OT | US | US |
Drug(s) used by person
| Event ID | CASEID | DRUG SEQ | ROLE COD | DRUGNAME | PROD AI | VAL VBM | ROUTE | DOSE VBM | CUM DOSE CHR | CUM DOSE UNIT | DECHAL | RECHAL | LOT NUM | EXP DT | NDA NUM | DOSE AMT | DOSE UNIT | DOSE FORM | DOSE FREQ |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 125244842 | 12524484 | 1 | PS | METFORMIN | METFORMIN HYDROCHLORIDE | 1 | Unknown | 1000 MG, UNK | U | 77095 | 1000 | MG | |||||||
| 125244842 | 12524484 | 2 | SS | METFORMIN | METFORMIN HYDROCHLORIDE | 1 | Unknown | 2500 MG, DAILY | U | 77095 | 2500 | MG | |||||||
| 125244842 | 12524484 | 3 | SS | EPINEPHRINE. | EPINEPHRINE | 1 | Intravenous (not otherwise specified) | U | 0 | INFUSION | |||||||||
| 125244842 | 12524484 | 4 | SS | NOREPINEPHRINE | NOREPINEPHRINENOREPINEPHRINE BITARTRATE | 1 | Intravenous (not otherwise specified) | U | 0 | INFUSION | |||||||||
| 125244842 | 12524484 | 5 | C | DOBUTAMINE | DOBUTAMINEDOBUTAMINE HYDROCHLORIDE | 1 | Intravenous (not otherwise specified) | U | 0 | INFUSION | |||||||||
| 125244842 | 12524484 | 6 | C | VANCOMYCIN | VANCOMYCIN | 1 | Intravenous (not otherwise specified) | U | 0 | INFUSION | |||||||||
| 125244842 | 12524484 | 7 | C | LEVOFLOXACIN. | LEVOFLOXACIN | 1 | Intravenous (not otherwise specified) | U | 0 | INFUSION | |||||||||
| 125244842 | 12524484 | 8 | C | METRONIDAZOLE. | METRONIDAZOLE | 1 | Intravenous (not otherwise specified) | U | 0 | INFUSION | |||||||||
| 125244842 | 12524484 | 9 | C | FUROSEMIDE. | FUROSEMIDE | 1 | Unknown | 40 MG, DAILY | U | 0 | 40 | MG | |||||||
| 125244842 | 12524484 | 10 | C | FUROSEMIDE. | FUROSEMIDE | 1 | Unknown | 80 MG, TWO TIMES A DAY | U | 0 | 80 | MG | BID | ||||||
| 125244842 | 12524484 | 11 | C | INSULIN | INSULIN NOS | 1 | Unknown | U | 0 | ||||||||||
| 125244842 | 12524484 | 12 | C | DIGOXIN. | DIGOXIN | 1 | Unknown | U | 0 | ||||||||||
| 125244842 | 12524484 | 13 | C | WARFARIN | WARFARIN | 1 | Unknown | U | 0 | ||||||||||
| 125244842 | 12524484 | 14 | C | SPIRONOLACTONE. | SPIRONOLACTONE | 1 | Unknown | U | 0 | ||||||||||
| 125244842 | 12524484 | 15 | C | METOPROLOL SUCCINATE. | METOPROLOL SUCCINATE | 1 | Unknown | U | 0 | ||||||||||
| 125244842 | 12524484 | 16 | C | METOLAZONE. | METOLAZONE | 1 | Unknown | U | 0 |
Indications of drugs used
| Event ID | CASEID | INDI DRUG SEQ | INDI PT |
|---|---|---|---|
| 125244842 | 12524484 | 1 | Product used for unknown indication |
| 125244842 | 12524484 | 3 | Product used for unknown indication |
| 125244842 | 12524484 | 4 | Product used for unknown indication |
| 125244842 | 12524484 | 5 | Product used for unknown indication |
| 125244842 | 12524484 | 6 | Product used for unknown indication |
| 125244842 | 12524484 | 7 | Product used for unknown indication |
| 125244842 | 12524484 | 8 | Product used for unknown indication |
| 125244842 | 12524484 | 9 | Congestive cardiomyopathy |
| 125244842 | 12524484 | 11 | Product used for unknown indication |
| 125244842 | 12524484 | 12 | Product used for unknown indication |
| 125244842 | 12524484 | 13 | Product used for unknown indication |
| 125244842 | 12524484 | 14 | Product used for unknown indication |
| 125244842 | 12524484 | 15 | Product used for unknown indication |
| 125244842 | 12524484 | 16 | Product used for unknown indication |
Outcome of event
| Event ID | CASEID | OUTC COD |
|---|---|---|
| 125244842 | 12524484 | DE |
| 125244842 | 12524484 | OT |
Reactions reported
| Event ID | CASEID | DRUG REC ACT | PT |
|---|---|---|---|
| 125244842 | 12524484 | Acidosis | |
| 125244842 | 12524484 | Agitation | |
| 125244842 | 12524484 | Anion gap increased | |
| 125244842 | 12524484 | Blood lactic acid increased | |
| 125244842 | 12524484 | Blood pressure decreased | |
| 125244842 | 12524484 | Death | |
| 125244842 | 12524484 | Dyspnoea | |
| 125244842 | 12524484 | Hyperlactacidaemia | |
| 125244842 | 12524484 | Lactic acidosis | |
| 125244842 | 12524484 | Metabolic acidosis | |
| 125244842 | 12524484 | Oliguria | |
| 125244842 | 12524484 | Respiratory acidosis | |
| 125244842 | 12524484 | Tachypnoea | |
| 125244842 | 12524484 | Toxicity to various agents |
Reporting Sources (this data is often not reported and may therefore be missing here)
| no results found |
Therapies reported
| no results found |